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Tractocile is a specialized, clinical-grade medication specifically engineered for the management of preterm labor. It contains Atosiban, a synthetic peptide that acts as a competitive antagonist of human oxytocin at the receptor level. This high-precision tocolytic works by precisely blocking the oxytocin receptors in the uterine myometrium, thereby inhibiting the frequency of uterine contractions and decreasing uterine muscle tone. It provides a foundational solution for delaying imminent pre-term birth, allowing critical time for the administration of corticosteroids (for fetal lung maturation) and transfer to a specialized neonatal care facility.
Tractocile is a specialized, clinical-grade medication specifically engineered for the management of preterm labor. It contains Atosiban, a synthetic peptide that acts as a competitive antagonist of human oxytocin at the receptor level. This high-precision tocolytic works by precisely blocking the oxytocin receptors in the uterine myometrium, thereby inhibiting the frequency of uterine contractions and decreasing uterine muscle tone. It provides a foundational solution for delaying imminent pre-term birth, allowing critical time for the administration of corticosteroids (for fetal lung maturation) and transfer to a specialized neonatal care facility.
Product Type: Oxytocin Receptor Antagonist (Tocolytic)
Active Ingredient: Atosiban (7.5mg/ml)
Manufacturer: Ferring Pharmaceuticals — Quality-Assured Global Standard
Pack Size: 0.9ml Vial (Initial Bolus) or 5ml Vial (Concentrate for Infusion)
Route: Intravenous (IV) Injection and Infusion
Availability: Strictly Hospital Use / Prescription Required (POM)
Suitable For: Pregnant women (weeks 24 to 33 of gestation)
Tractocile is the primary clinical choice for the stabilization of premature labor:
Delay of Imminent Pre-term Birth: Inhibiting active labor contractions in women with a gestational age between 24 and 33 completed weeks.
Fetal Lung Maturation: Gaining 24 to 48 hours of pregnancy prolongation to allow for full steroid efficacy (e.g., Dexamethasone).
In-Utero Transfer: Stabilizing the mother to ensure a safe transfer to a tertiary hospital with a Neonatal Intensive Care Unit (NICU).
Gestation Window: Tractocile should only be used between 24 and 33 completed weeks of pregnancy. Contraindications: Do NOT use if there is premature rupture of membranes (PROM) after 30 weeks, suspected intrauterine infection, placenta praevia, abruptio placentae, or fetal distress requiring immediate delivery. Heart Health: While generally well-tolerated, monitor the mother for signs of pulmonary edema or tachycardia, especially if used alongside other tocolytics. Eclampsia: Do not use in cases of severe pre-eclampsia or eclampsia that necessitate immediate delivery.
For maximum efficacy, Tractocile must be administered in a continuous three-stage clinical protocol by a trained obstetric professional.
The Three-Step Dosage Regimen:
Initial Bolus: 0.9ml (6.75mg) injected slowly over 1 minute into a vein.
High-Dose Infusion: 300 micrograms/min for 3 hours.
Maintenance Infusion: 100 micrograms/min for up to 45 hours.
Clinical Tips:
Preparation: For the infusion, the 5ml concentrate must be diluted in 0.9% Sodium Chloride or Ringer's Lactate solution.
Duration: The total duration of treatment should not exceed 48 hours. The total dose for a full course should not exceed 330mg.
Monitoring: Continuous monitoring of uterine contractions and fetal heart rate is mandatory throughout the infusion.
The most common side effect is nausea. Other potential effects include headache, dizziness, hot flushes, or vomiting. Less common is tachycardia (fast heartbeat) or hypotension (low blood pressure). Unlike other tocolytics (like Salbutamol), Tractocile has significantly fewer cardiovascular side effects for the mother. If you experience sudden chest pain or difficulty breathing, alert the medical team immediately.
Q: Does it "Stop" labor permanently?
A: No. Tractocile is designed to delay labor for about 48 hours. This time is used to provide other treatments that improve the baby's chances of survival after birth.
Q: Is it safe for the "Baby"?
A: Clinical studies have shown no direct ill effects on the fetus or the newborn. It is specifically used to give the baby more time to develop.
Q: Can the treatment be "Repeated"?
A: If labor contractions return, a repeat course of Tractocile can be started, but the total number of re-treatments should be limited based on clinical assessment.
Store in a refrigerator at 2°C to 8°C. Do not freeze. Store in the original package to protect from light. Once the vial is opened or diluted, it should be used immediately. Keep out of reach of children.
Authentic Ferring (Original) premium hospital-grade stock.
Expert guidance on "Cold-Chain" delivery to ensure medication potency.
Licensed pharmacists available for clinical protocol consultation.
Fast, reliable delivery to maternity hospitals and clinics across Nigeria.
Order Tractocile from Sanlive Pharmacy for professional-grade management of preterm labor.
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